Orgestra
Organoid technologies for disease modelling, drug discovery and development for rare diseases.
About the Orgestra project
We are an EU funded MSCA Joint Doctoral network that will train thirteen doctoral candidates in developing personalized disease models using stem cell-derived organoids for rare diseases, including the lung and kidney diseases, cystic fibrosis and cystinosis.
Research will aim to identify pathogenetic mechanisms, druggable targets, and drug mode of action for effective and innovative treatment strategies and to classify the pathway to clinic. We will also address ethical and regulatory issues to foster acceptance and implementation of organoid models and develop a living technologies toolset to enable a swift transfer from bench to bedside.
ORGESTRA is a four-year project funded by the EC HORIZON–MSCA-2023-DN-JD Grant Agreement No 101120108, coordinated by the University of Utrecht. The project starts 1st January 2024 and will end in December 2027.
The network is made up of fourteen partners from seven European countries providing international, intersectoral and interdisciplinary training that brings together molecular biologists, engineers, pharmacologists, clinicians, epidemiologists and ethicists, to give each of our doctoral candidates a unique, joint-doctoral training experience complemented by a rich network training programme.
Meet our Doctoral Candidates
Our network partners are
Associate Partners undertaking training/secondments or degree awarding include:
Latest news
1st August is World RNA day
Did you know why August 1st is celebrated as the World RNA Day? The date AUG 1 is a meaningful tribute to the molecular basis of life. AUG is the start codon in messenger RNA (mRNA), signaling the initiation of translation, and 1 marks its position as the first...
ORGESTRA DCs outreach to high schools
This month two of our DCs have been undertaking outreach activities to high school students at two schools in Germany. Martje Grensemann DC1 explains more: "Last week, I visited my former high school, Gymnasium am Mühlenberg in Bad Schwartau, and gave a full-day...