Doctoral Candidate Projects
ORGESTRA is a Marie Skłodowska-Curie Joint Doctorate Network training 13 PhD candidates to conduct advanced research that addresses critical challenges in the field of organoid technologies for disease modelling, drug discovery and development for rare diseases. Our innovative and ambitious joint-PhD program will train highly qualified young scientists in new scientific and technological knowledge. At the end of your PhD, you will obtain joint/double PhD diplomas from two reputed universities within the ORGESTRA network.
Find out more about our PhD projects here:
Improving kidney organoids for pathophysiological studies and mechanistic insights
Urine progenitors for kidney disease modelling
Upscaling and standardisation of organoids culturing
Colon organoids for genetic kidney disease modeling and drug screening
Molecular biology and high content screening of airway epithelia
Primary airway cell culture, gene editing, and functional analysis for rare disease drug discovery and validation
Antisense oligonucleotide and RNA therapies in organoids for cystic fibrosis and cystinosis
mRNA-based therapeutics for cystic fibrosis and cystinosis
Viral vector-based therapeutics to restore gene function in cell- and organoid-models for cystinosis
Gene therapies for cystinosis and cystic fibrosis
Linking in silico trials to organoids data and innovative trial design
Estimand framework involving Bayesian principles on organoids data for clinical trial outcomes and models
Ethical, legal and social aspects of organoid technologies for rare diseases